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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: J Immunol. 2012 Jun 25;189(3):1154–1161. doi: 10.4049/jimmunol.1200123

Figure 2.

Figure 2

Themis1 or Themis2 transgene expression restores positive selection in AND TCR transgenic Themis1−/− mice. Analysis by flow cytometry of thymocytes and lymph nodes T cells in Themis1+/+, Themis1−/−, Themis1−/−; Themis1tg, Themis1−/−; Themis2tg mice expressing MHC class II-restricted (AND) TCR. Representative two parameter plots (n=4) show CD4 versus CD8 staining on total thymocytes or lymph node cells. Numbers indicate percentage of cells in the indicated quadrant. Single parameter histogram plots show AND TCR staining (Vα11) on total thymocytes or peripheral lymph nodes cells.