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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: J Pediatr Surg. 2012 Jul;47(7):1369–1379. doi: 10.1016/j.jpedsurg.2012.02.001

Figure 5. E-cadherin positive cells are not detected within the duodenal atretic precursor at E12.0 (CS17).

Figure 5

E-cadherin staining of the duodenal atretic precursor of an Fgfr2IIIb-/- embryo at E12.0 (A-D) and in a stage matched wild-type embryo (E-H). Images are organized in a rostral to caudal fashion. A. E-cadherin positive cells are absent in the atretic precursor (AP) region (blue arrow) and present in the region distal to this (B and C, white arrow) and in the C- loop of the duodenum (D). In contrast E-cadherin positive cells are seen lining a continuous luminal structure throughout the duodenum proximal and distal to the C-loop in the wild-type control (E-H). (Bars indicate 100μM). Yellow arrows indicate pancreatic duct tissue. Red arrow indicates colon. Pink arrow indicates pylorus. Dist. Indicates distal duodenum beyond the C-loop.