Table 5.

Annotation of a set of seven genes uniquely identified by EpiPredictor-CG

Gene	Verified function in Drosophila	Vertebrate homologue
inv	A newly experimentally validated PRE was found to exist in the inv locus (38). It is important for hindgut development (76)
wg	Embryogenesis (Wingless/Wnt signaling pathway) (77)	WNT1: predicted as PcG target in human (7); involved in embryogenesis and cancer (86)
nub	Embryogenesis, neurogenesis (78–80)
pdm2	Important for a variety of cell fate decisions in development (81)
dac	Induce ectopic eye development (82)	DACH-1: predicted as PcG target in human (7)
Gsc	groucho-dependent repression in embryo (83)	GSC: predicted as PcG target in human (7)
tup	Imaginal disc development (84), key component in early cardiogenesis (85)	ISL1: predicted as PcG target in human (7)