Table 1.
Ontology groups enriched within the set of the 100 most up-regulated diploid genes identified using the Functional Annotation Chart in NIH DAVID, and level 5 GOterms
| Category | Term | Count | Fold Enrichment | Bonferroni |
|---|---|---|---|---|
| GOTERM_MF_5 | serine-type peptidase activity | 17 | 7.54 | 2.76E-09* |
| GOTERM_MF_5 | serine-type endopeptidase activity | 16 | 7.81 | 8.20E-09* |
| GOTERM_BP_5 | proteolysis | 22 | 4.74 | 6.31E-08* |
| GOTERM_MF_5 | endopeptidase activity | 18 | 5.38 | 1.11E-07* |
| GOTERM_BP_5 | chitin metabolic process | 6 | 8.28 | 0.12 |
| GOTERM_BP_5 | aminoglycan metabolic process | 6 | 6.65 | 0.28 |
| GOTERM_MF_5 | exopeptidase activity | 5 | 6.45 | 0.16 |
| GOTERM_CC_5 | integral to membrane | 10 | 2.29 | 0.13 |
| GOTERM_CC_5 | intrinsic to membrane | 10 | 2.25 | 0.15 |
| GOTERM_BP_5 | positive regulation of translation | 2 | 31.47 | 1.00 |
| GOTERM_MF_5 | serine-type exopeptidase activity | 2 | 24.85 | 0.87 |
Significantly enriched (Bonferroni-adjusted, P < 0.001) ontology groups are indicated in bold. For a detailed list of genes, see Supplementary Table S3.