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. Author manuscript; available in PMC: 2012 Jul 23.
Published in final edited form as: Lab Chip. 2011 Apr 26;11(12):2060–2065. doi: 10.1039/c0lc00539h

Fig. 4.

Fig. 4

A. Demonstration of a wound-healing/migration assay with variable spacing between the two cell populations. The upper right diagram represents the microfluidic device geometry. B. Multiple contrast enhanced movie-frames superimposed to illustrate the flow paths of cells being patterned in the wound-healing/migration device. C. RFP and GFP MCF7 cells patterned into a three-flow device. D. Osteoblasts (MC3T3-E1) and prostate cancer cells (LNCaP) are patterned within in a collagen matrix. The inset shows collagen fibers formed after polymerization using phase contrast imaging. E. Illustration of the arraying ability of the method for high-throughput screening (HTS) applications. All images were taken within 15 min of seeding.