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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Neuroimage. 2012 Feb 1;62(4):2281–2295. doi: 10.1016/j.neuroimage.2012.01.117

Figure 2.

Figure 2

State and trait components of nicotine addiction. (A) Two of the seven resting state networks that showed enhanced connectivity under nicotine relative to placebo administration in minimally deprived (~4.5hrs) smokers. Left image shows enhanced rsFC between a dorsal ACC (dACC) seed (blue oval) and a region encompassing the superior parietal lobe and post-central gyrus. Right image shows enhanced rsFC between a mid cingulate cortex (MCC) seed and a region encompassing the post-central gyrus and inferior parietal lobe. (B) Negative correlation between scores on the Fagerström Test for Nicotine Dependence (FTND) and rsFC strength in smokers between the right striatum (blue) and a dACC seed in minimally deprived (grey triangles) and nicotine sated (red diamonds) conditions. (Reproduced from Hong et al., 2009).