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(A) Serum total tryptase levels are higher in PAH than controls. Total serum tryptase levels are higher in PAH compared to controls indicating greater total numbers of mast cells in PAH. Box plots indicate median values, upper and lower quartiles. (B) Serum total tryptase levels correlate with brain natriuretic peptide (BNP). Total tryptase levels are related to disease severity assessed by BNP.
