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. Author manuscript; available in PMC: 2013 Jul 20.
Published in final edited form as: ACS Chem Biol. 2012 Jul 3;7(7):1139–1151. doi: 10.1021/cb300119g

Figure 1.

Figure 1

Antibody Recruiting Small Molecules (ARMs). ARMs are bifunctional small molecules that function by forming ternary complexes with disease-relevant targets and endogenous antibodies. Ternary complex assembly leads to the activation of immune effector functions, followed by immune-mediated cytotoxicity and/or clearance of disease-causing species