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Differential fear conditioning in NPY KO mice using a visual (CS−) and an auditory (CS+) stimulus. (A) Accelerated acquisition of conditioned fear in NPY KO mice compared to WT, (B) both, WT and NPY KO mice display higher % freezing to CS+ compared to CS− at fear testing 24 h after acquisition, demonstrating discrimination of two more distinct CS. Values are means ± SEM, repeated two-way anova with Bonferroni post hoc test, **P < 0.01, ***P < 0.001.
