Table 1.
Specification of drugs used in this study
| Name | Synonym | Supplier | Main target(s) |
|---|---|---|---|
| Bosutinib | SKI-606 | ChemieTek | ABL, SRC |
| Dasatinib | BMS-354825 | ChemieTek | ABL, SRC, KIT, BTK, LYN |
| Erlotinib | OSI-774 | ChemieTek | EGFR, Her2 |
| Gefitinib | ZD1389 | ChemieTek | EGFR, Her2 |
| Imatinib | STI-571 | ChemieTek | ABL, KIT, PDGFR |
| Lapatinib | GW572016 | ChemieTek | EGFR, Her2 |
| Masitinib | AB1010 | LC Laboratories | KIT, PDGFR, LYN |
| Midostaurin | PKC412 | LC Laboratories | FLT3, KIT |
| Nilotinib | AMN107 | ChemieTek | ABL, KIT, PDGFR |
| Sorafenib | BAY 43-9006 | ChemieTek | Raf, VEGFR, KIT |
| Sunitinib | SU11248 | ChemieTek | PDGFR, VEGFR, KIT |
| Everolimus | RAD001 | ChemieTek | mTOR |
| NVP-BEZ235 | BEZ235 | ChemieTek | mTOR, PI3 kinase |
| Tozasertib | VX-680, MK-0457 | ChemieTek | Aurora Kinase A, KIT |
| Vorinostat | SAHA | ChemieTek | HDAC |
BTK, Bruton's tyrosine kinase; EGFR, epidermal growth factor receptor; PDGFR, platelet-derived growth factor receptor; VEGFR, vascular endothelial growth factor receptor; mTOR, mammalian target of rapamycin; PI3 kinase, phosphoinositide 3 kinase; HDAC, histone deacetylase.