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. Author manuscript; available in PMC: 2012 Jul 23.
Published in final edited form as: Intensive Care Med. 2009 Sep 15;36(1):148–156. doi: 10.1007/s00134-009-1643-9

Fig. 1.

Fig. 1

a Compares the effects of B. anthracis cell wall administered as a bolus in doses of 10, 20, 40, 80 or 160 mg/kg to a diluent (control) on the proportion of animals surviving. Based on the results shown in a, b–h show the effects of either nonlethal doses (10 and 20 mg/kg) or lethal doses (40, 80 and 160 mg/kg) of B. anthracis cell wall bolus combined compared to control on: the serial mean (±SEM) changes from baseline in mean arterial blood pressure (MBP, mmHg, b) and heart rate (HR, BPM, c) measured q15 min from 0 to 1 h, q2 h from 2 to 8 h and q4 h from 12 to 24 h and serial mean (±SEM) arterial lactates (d), arterial–alveolar oxygen gradients (A-aO2, e) and circulating neutrophils (f), lymphocytes (g) and platelets (h) measured at 4, 8 and 24 h