Table 2. Genotype Frequency ORs of Transsexualism Among ERβ and CYP19 Genes.
Locus | Repeat | Genotype | Transsexuals n = 112 (%) | Control Subjects n = 258 (%) | OR (95% CI) | p |
---|---|---|---|---|---|---|
ERβ | CA | SS | 75 (67.6) | 165 (64.0) | 1.00 (reference) | .77 |
SL | 32 (28.8) | 83 (32.2) | 1.15 (.35–3.79) | .81 | ||
LL | 4 (3.6) | 10 (3.8) | .96 (.28–3.30) | .95 | ||
CYP19 | TTTA | SS | 31 (29.8) | 76 (29.5) | 1.00 (reference) | .87 |
SL | 51 (49.0) | 133 (51.5) | .91 (.47–1.75) | .77 | ||
LL | 22 (21.2) | 49 (19.0) | .45 (.47–1.55) | .60 |
OR, odds ratio; CI, confidence interval; ERβ, estrogen receptor beta; CYP19, aromatase; LL, two long alleles; SL, one short and one long allele; SS, two short alleles.