Table 3.
ZF protein–DNA interaction matrix of counts for interacting amino acid - base pairs within distances < 3.3Å as observed in 25 X-ray and 5 NMR structures. Only significant amino acid and nucleotide positions are shown; the top number gives the combined total of primary and complimentary chain contacts, and the bottom numbers give in parentheses the number of primary chain contacts followed by the number of complimentary DNA chain contacts. The seven most frequent contacts are highlighted; canonical contacts have darker shadings.
| position | Base | ||||
|---|---|---|---|---|---|
| b4 | b3 | b2 | b1 | ||
| amino acid | a−1 | 26 (16/10) | 81 (81/0) | 11 (11/0) | 0 |
| a2 | 61 (2/59) | 21 (3/18) | 3 (0/3) | 1 (1/0) | |
| a3 | 0 | 1 (1/0) | 79 (79/0) | 5 (5/0) | |
| a6 | 2 (0/2) | 1 (0/1) | 27 (13/14) | 58 (58/0) | |