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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Hypertension. 2012 Apr 16;59(6):1170–1178. doi: 10.1161/HYPERTENSIONAHA.111.186072

Figure 6. Chronic TAC and hypoxia increased expression of genes related to lung fibrosis and inflammation.

Figure 6

(A,B) Expression of TGF-1β; (A,C) Collagen-I; (A,D) collagen-III; (A,E) TNFα; and (A,F,G) adhesion molecules ICAM and VECAM in lung tissues from control group, TAC-induced M-HF or HF groups. (H) The diagram shows the potential mechanism of TAC-induced pulmonary remodeling, pulmonary hypertension and mortality. *p<0.05 vs control group; #p<0.05 vs. corresponding M-HF group.