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. 2012 Jun 8;19(4):541–556. doi: 10.1530/ERC-12-0007

Table 1.

The ratio of the expression of miR-200c, ZEB1, ZEB2, TIMP2, FBLN5, and VEGFA in each leiomyoma (L) over its own paired myometrium (M) from untreated group (n=43) representing to follicular (Follicular; n=12) and luteal (Luteal; n=19) phases of the menstrual cycle and women experiencing AUB (n=12) and those who received GNRHa (n=9), Depo (n=17), and those taking OCPs (n=7). The ratio represents the number of leiomyoma over its own paired myometrium expressing elevated (up) or lower (down) levels of miR-200c and its target genes at 1.3-fold change cutoff with percentage shown in parentheses for each group and total number of paired tissues analyzed (n value)

L/M Follicular Luteal AUB GNRH Depo OCP
miR-200c
 Up 3/12 (0.25) 6/19 (0.316) 1/12 (0.083) 0 6/17 (0.353) 3/7 (0.429)
 Down 8/12 (0.667) 11/19 (0.579) 10/12 (0.833) 7/9 (0.778) 8/17 (0.471) 2/7 (0.286)
 n value 12 19 12 9 17 7
ZEB1
 Up 2/11 (0.182) 3/19 (0.158) 5/12 (0.417) 1/9 (0.111) 3/14 (0.214) 0
 Down 4/11 (0.364) 6/19 (0.316) 3/12 (0.25) 7/9 (0.778) 4/14 (0.286) 4/5 (0.8)
 n value 11 19 12 9 14 5
ZEB2
 Up 1/9 (0.111) 3/19 (0.158) 1/12 (0.083) 2/9 (0.222) 2/14 (0.143) 0
 Down 7/9 (0.778) 9/19 (0.474) 10/12 (0.833) 5/9 (0.556) 8/14 (0.571) 4/4 (1)
 n value 9 19 12 9 14 4
TIMP2
 Up 1/9 (0.111) 1/16 (0.063) 3/12 (0.25) 0 3/11 (0.273) 0
 Down 5/9 (0.556) 8/16 (0.5) 4/12 (0.333) 4/6 (0.667) 2/11 (0.182) 3/3 (1)
 n value 9 16 12 6 11 3
FBLN5
 Up 1/7 (0.143) 1/16 (0.063) 3/12 (0.25) 0 3/11 (0.273) 0
 Down 2/7 (0.286) 7/16 (0.438) 8/12 (0.667) 5/6 (0.833) 6/11 (0.545) 3/3 (1)
 n value 7 16 12 6 11 3
VEGFA
 Up 5/9 (0.556) 3/16 (0.188) 8/12 (0.667) 1/6 (0.167) 0 2/3 (0.667)
 Down 2/9 (0.222) 6/16 (0.375) 3/12 (0.25) 4/6 (0.667) 5/11 (0.455) 1/3 (0.333)
 n value 9 16 12 6 11 3