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. 2012 Aug;23(8):1389–1397. doi: 10.1681/ASN.2012020122

Table 3.

Conventional and instrumental variable estimates of the risk difference (on pump minus off pump) associated with on-pump versus off-pump CABG

Event Estimated Risk Difference per 100 Patients (95% CI)
Conventional Unadjusted Conventional Propensity Weighteda Unadjusted Center Preference Analysis Adjusted Center Preference Analysis
Overall cohort
 death or RRT 0.20 (0.12, 0.27)b 0.28 (0.21, 0.36)b 0.18 (0.02, 0.34)c 0.03 (−0.21, 0.26)
 death 0.10 (0.04, 0.16)d 0.15 (0.09, 0.21)b 0.06 (−0.08, 0.20) −0.07 (−0.27, 0.13)
 RRT 0.13 (0.08, 0.18)b 0.18 (0.13, 0.24)b 0.18 (0.07, 0.29)d 0.13 (−0.03, 0.29)
eGFR ≥90
 death or RRT 0.07 (−0.03, 0.18) 0.05 (-0.06, 0.16) 0.26 (0.06, 0.46)d 0.10 (−0.21, 0.41)
 death 0.05 (−0.05, 0.14) 0.04 (-0.06, 0.13) 0.20 (0.02, 0.38)c 0.08 (−0.20, 0.36)
 RRT 0.07 (0.02, 0.13)c 0.05 (-0.01, 0.11) 0.09 (−0.02, 0.20) 0.08 (−0.06, 0.23)
eGFR 60–89
 death or RRT 0.16 (0.08, 0.25)b 0.14 (0.05, 0.23)d 0.01 (−0.18, 0.20) −0.26 (−0.57, 0.06)
 death 0.10 (0.03, 0.18)c 0.09 (0.02, 0.17)c −0.06 (−0.23, 0.12) −0.28 (−0.57, 0.00)
 RRT 0.07 (0.02, 0.12)d 0.05 (−0.00, 0.11) 0.09 (−0.01, 0.19) 0.01 (−0.17, 0.19)
eGFR 30–59
 death or RRT 0.58 (0.38, 0.79)b 0.66 (0.45, 0.87)b 0.43 (−0.04, 0.90) 0.28 (−0.38, 0.94)
 death 0.20 (0.03, 0.37)c 0.30 (0.12, 0.47)b 0.21 (−0.16, 0.59) 0.16 (−0.34, 0.65)
 RRT 0.46 (0.31, 0.61)b 0.47 (0.31, 0.62)b 0.36 (0.03, 0.70)c 0.22 (−0.32, 0.75)
eGFR 15–29
 death or RRT 3.65 (2.20, 5.10)b 3.66 (2.14, 5.18)b 4.73 (1.64, 7.82)d 4.60 (0.53, 8.68)c
 death 1.73 (0.90, 2.56)b 1.92 (1.06, 2.78)b 1.14 (−0.70, 2.98) −0.36 (−3.60, 2.88)
 RRT 2.76 (1.41, 4.11)b 2.79 (1.37, 4.20)b 4.02 (1.17, 6.87)c 4.49 (1.07, 7.91)d
a

Inverse probability weighted estimates after balancing treatment groups using propensity score.

b

P value <0.001.

c

P value <0.05.

d

P value <0.01.