Skip to main content
. 2012 Jul 17;61(8):2105–2113. doi: 10.2337/db11-1546

FIG. 2.

FIG. 2.

Immunostaining for collagen IV (a–f) and fibronectin (h–m) in nondiabetic control (C) and diabetic (D) apoE KO and RAGE apoE double-KO mice, with and without treatment. ApoE C (a, h); RAGE apoE KO (b, i); apoE D (c, j); diabetic RAGE apoE KO (d, k); diabetic RAGE apoE KO alagebrium (A) 1 mg/kg/day (e, l); diabetic RAGE/apoE KO quinapril (Q) 30 mg/kg/day (f, m). Scale bar = 20 μm. Digital quantification of glomerular staining for collagen IV (g) and fibronectin (n) for n = 6–10 per group. *P < 0.05 vs. apoE KO. §P < 0.05 vs. diabetic apoE. ¶P < 0.05 vs. RAGE apoE KO. #P < 0.05 diabetic RAGE apoE KO vs. diabetic RAGE apoE KO + quinapril. †P < 0.05 diabetic RAGE apoE KO vs. diabetic RAGE apoE KO + alagebrium. (A high-quality color representation of this figure is available in the online issue.)