FIG. 3.
Gene and protein expression of inflammation markers CD11b and ICAM-1 in glomeruli from nondiabetic control (C) and diabetic (D) apoE KO and RAGE apoE double-KO mice, with and without treatment, as measured by RT-PCR and ELISA. Gene expression of CD11b (A), relative protein content of CD11b (B), gene expression of ICAM-1 (C), and relative protein expression of ICAM-1 (D) for n = 6–10 per group. *P < 0.05 vs. apoE KO. §P < 0.05 vs. diabetic apoE. ¶P < 0.05 vs. RAGE apoE KO. #P < 0.05 diabetic RAGE apoE KO vs. diabetic RAGE apoE KO + quinapril. †P < 0.05 diabetic RAGE apoE KO vs. diabetic RAGE apoE KO + alagebrium.
