FIG. 1.

mRNA induction of antiviral genes, cytokines, and chemokines in human pancreatic islets upon CVB3 infection. A: Human islets were infected at a multiplicity of infection (MOI) of 10, and virus titers were determined by end point titration at the indicated times pi. B: Images of islets taken 48 h pi. C: Human islets were infected with CVB3 or UV-inactivated CVB3 (MOI 10) or were mock infected, and at indicated times, mRNA induction of indicated genes was determined using qPCR. D: mRNA induction of indicated genes was determined by qPCR in islets infected as in C. Data are representative examples of at least three experiments using different donors. AU, arbitrary unit.