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. 2012 Jul 23;7(7):e41585. doi: 10.1371/journal.pone.0041585

Figure 1. The effect of MC-12 on DSS- and TNBS-induced colitis in mice.

Figure 1

Mice (7/group) received 2% DSS in drinking water or 2.5% TNBS intra-colonically to induce colitis and were treated with vehicle or MC-12 given IP, PO or IR. A: The body weight of mice of DSS model during treatment by IP, PO or IR, expressed as percentage of baseline (day 0). B: The colon length of DSS model with MC-12 treatments by IP, PO or IR. C: The body weight of mice of TNBS model during treatment, expressed as percentage of baseline (day 0). D: The colonic length of mice of TNBS model in three treatment groups. These studies were repeated at least once giving similar results. Values are mean ± SEM. *, statistically significant difference from the vehicle-treated group.