Table 3. Histopathology by light microscopy, myocyte cross-sectional area, collagen value fraction and determination of metalloproteinases -2 and -9 activation.
Group Cn = 7 | Group T(-)n = 7 | P | |
CSA (µm2) | 238.3±24.2 | 196.3±29.7* | 0.013 |
CVF (%) | 1.37±0.8 | 1.34±1.3 | 0.955 |
MMP2 A/I | 0.51±0.1 | 0.51±0.1 | 0.870 |
MMP9 A/I | 0.65±0.7 | 0.60±0.4 | 0.898 |
Group C: control animals, Group T (-): taurine-deficient animals; CSA: myocyte cross sectional area; CVF: collagen value fraction; MPP2 A/I: ratio of the active and inactive forms of metalloproteinase 2; MPP9 A/I: ratio of the active and inactive forms of metalloproteinase 9. Data are expressed as means ± standard deviations or medians (quartile 1 - quartile 3). Bold values indicate statistical significance (P≤0.05).