Figure 3. The motor function of the mice was examined prior to, 24 and 72 h after ischemic onset.

A) 24 h after ischemia, all mice demonstrated significant functional deficits that were not affected by sulforaphane treatment. (mean±SD, n = 8–12, t-test or one way ANOVA *p≤0.05, **p≤0.001, ***p≤0.0001; solid black circle vehicle, solid grey circle 5 mg/kg sulforaphane, open box 50 mg/kg sulforaphane). B) 72 h after ischemia, mice treated with sulforaphane were able to complete the round beam task compared to vehicle. All other behavioural outcome measurements had returned to pre stroke baseline levels. (mean±SD, n = 8–12, solid black line vehicle, solid grey line 5 mg/kg sulforaphane, dashed grey line 50 mg/kg sulforaphane, *** F(2,48) = 53.21, p≤0.0001).