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. 2012 Jul 23;7(7):e41035. doi: 10.1371/journal.pone.0041035

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Niu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Annexin V staining in (A) control SP cells (B) SP cells treated with LMWH (C) SP cells treated with cisplatin and (D) SP cells treated with LMWH plus cisplatin. (E) Quantification of apoptosis rates in A549/DDP SP cells induced by LMWH and DDP. No significant difference was observed in control and LMWH-treated SP cells. Apoptosis induced by LMWH plus DDP was significantly higher than DDP alone (p<0.05). (F) The inhibition rate of LMWH-treated A549/DDP SP cells in MTT assay. No significant difference was observed in inhibition rate of control and LMWH-treated SP cells.