Figure 4. AtxA enzymatic activity is membrane curvature dependent.

Relative enzymatic activity of AtxA on phospholipid vesicles of different diameters (50 nm, 100 nm and 200 nm) is shown. The measurements were normalized to the phospholipolytic activity on 100 nm vesicles. The bars represent standard deviation of three independent measurements. The differences are statistically significant based on the unpaired t-test at 95% confidence interval.