Table 2. Description of CTSS variability in subcohort and cases.

CTSS
		random subcohort			Cases
		n	frequency	pHWE	n	frequency	pHWE
rs7511673	A/A	2382	0.36	0.93	2016	0.36	0.49
	A/T	3142	0.48		2699	0.48
	T/T	1041	0.16		869	0.16
	A	7906	0.60		6731	0.60
	T	5224	0.40		4437	0.40
rs11576175	G/G	5341	0.81	0.39	4571	0.82	0.84
	G/A	1155	0.18		960	0.17
	A/A	70	0.01		52	0.01
	G	11837	0.90		10102	0.90
	A	1295	0.10		1064	0.10
rs10888390	G/G	2721	0.41	0.69	2320	0.42	0.63
	G/A	2999	0.46		2544	0.46
	A/A	844	0.13		717	0.13
	G	8441	0.64		7184	0.64
	A	4687	0.36		3978	0.36
rs1136774	A/A	1833	0.28	0.76	1606	0.29	0.15
	A/G	3283	0.50		2727	0.49
	G/G	1448	0.22		1250	0.22
	A	6949	0.53		5939	0.53
	G	6179	0.47		5227	0.47

Genotype and allele counts, genotype and allele frequencies and Hardy Weinberg Equilibrium test p-values for each SNP in the subcohort and in the cases respectively.