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. 2012 Jul 23;7(7):e41299. doi: 10.1371/journal.pone.0041299

Figure 3. Gonadal steroids differentially regulate the expression of mERα in lactotropes and somatotropes in vivo.

Figure 3

OVX female rats were injected for two consecutive days with vehicle (VEH), 17β-estradiol (E2), progesterone (P4) or E2+P4 and euthanized on the third day. Dispersed anterior pituitary cells were immunostained for both mERα and PRL or GH and analyzed by flow cytometry. Each column represents the mean ± SE of anterior pituitary cells (A), lactotropes (B) or somatotropes (C) expressing mERα (n = 3−4 animals per group). *p<0.05 vs respective control without P4; ∧p<0.05 vs respective control without E2, two-way ANOVA followed by Tukey’s test.