Table 7. Rectal temperature and heart rate on the day of the 30-min coronary occlusion in Phase III study.
| Group | Pre-occlusion | Occlusion | Reperfusion | ||||
| 5 min | 15 min | 30 min | 5 min | 10 min | 15 min | ||
| Temperature (°C) | |||||||
| Group XI (IP+/+, non-PC, n = 16) | 36.9±0.1 | 37.2±0.1 | 37.0±0.1 | 37.0±0.0 | 37.0±0.0 | 37.0±0.1 | 36.8±0.0 |
| Group XII (IP+/+, late PC, n = 13) | 36.9±0.1 | 37.2±0.1 | 37.1±0.1 | 37.0±0.1 | 37.1±0.1 | 37.1±0.1 | 37.1±0.1 |
| Group XIII (IP−/−, non-PC, n = 12) | 37.0±0.1 | 37.2±0.1 | 36.9±0.1 | 37.1±0.1 | 36.9±0.1 | 36.9±0.0 | 36.9±0.1 |
| Group XIV (IP−/−, late PC, n = 12) | 37.1±0.1 | 37.1±0.0 | 37.1±0.0 | 37.0±0.1 | 37.1±0.1 | 37.0±0.1 | 37.0±0.1 |
| Heart rate (beats/min) | |||||||
| Group XI (IP+/+, non-PC, n = 16) | 506±12 | 512±12 | 495±9 | 502±11 | 521±12 | 518±15 | 595±16 |
| Group XII (IP+/+, late PC, n = 13) | 543±16 | 577±15 | 576±17 | 577±16 | 594±13 | 592±10 | 590±19 |
| Group XIII (IP−/−, non-PC, n = 12) | 505±17 | 498±17 | 469±19 | 472±13 | 495±15 | 475±13 | 498±17 |
| Group XIV (IP−/−, late PC, n = 12) | 536±13 | 569±16 | 553±16 | 529±24 | 555±17 | 563±19 | 567±19 |
Data are means ± SEM. Measurements of rectal temperature and heart rate were taken before the 30-min coronary occlusion (pre-occlusion), at 5, 15 and 30 min into the 30-min occlusion, and at 5, 15 and 30 min after reperfusion. Rectal temperature was continuously monitored and carefully controlled throughout the experiment, as detailed in the text.