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. 2012 Jul 23;7(7):e41141. doi: 10.1371/journal.pone.0041141

Table 3. Antimicrobial testing of NlysNlysNlys based lipopeptoids.

Compound Organism CTAC C11-NlysNlysNlys C14-NlysNlysNlys C16-NlysNlysNlys C20-NlysNlysNlys F11-NlysNlysNlys C11-NhargNhargNharg C14-NhargNhargNharg C16-NhargNhargNharg C20-NhargNhargNharg
S.aureus b 1 512 32 16 16 32 128 16 8 8
MRSA c 1 512 64 32 16 32 128 16 16 16
MSSE d 0.5 512 32 8 8 32 64 8 8 8
MRSE e 2 512 16 8 8 32 256 16 8 8
E. faecalis f 1 512 64 32 16 64 512 32 16 16
E. faecium g 0.5 256 64 32 16 64 256 16 16 8
S.pneumoniae h 2 >512 128 128 64 128 512 64 64 64
E.coli i 16 >512 128 32 32 64 >512 64 16 64
E.coli j 32 >512 128 64 32 64 >512 64 32 64
E.coli k 16 >512 128 64 32 128 >512 64 32 32
P.aeruginosa l 128 >512 512 128 128 128 >512 256 64 128
P.aeruginosa m 64 >512 512 128 64 256 >512 128 64 128
S. maltophilia n 32 >512 >512 256 64 >512 >512 256 128 64
A. baumannii o 32 >512 512 256 64 >512 >512 256 128 64
K.pneumoniae p 16 >512 512 128 64 >512 >512 256 256 64
Haemolysis 77.05 0.67 2.19 67.69 68.29 8.13 0.71 20.34 30.80 71.50
a

MIC, reported in µg/mL.

b

ATCC 29213.

c

ATCC 33592.

d

81388 CANWARD 2008.

e

CAN-ICU 61589.

f

ATCC 29212.

g

ATCC 27270.

h

ATCC 49619.

i

ATCC 25922.

j

CAN-ICU 61714.

k

CAN-ICU 63074.

l

ATCC 27853.

m

CAN-ICU 62308.

n

CAN-ICU 62584.

o

CAN-ICU 63169.

p

ATCC 13883.

q

Percent haemolysis at 100µg/mL of compound.