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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: J Invest Dermatol. 2012 May 10;132(8):2067–2075. doi: 10.1038/jid.2012.112

Figure 4.

Figure 4

KC-Tie2 mice are pro-thrombotic. KC-Tie2 and control mice underwent experimental thrombosis; carotid artery blood flow was monitored continuously with a vascular flow probe, time to occlusion, defined as cessation of blood flow for 20 min, was recorded (a). Mean time (± SEM) to occlusive thrombus formation in control mice was 53 ± 8 minutes (n=10), and was shortened significantly in KC-Tie2 mice (19 ± 3 minutes; n=9; P=0.002). H&E stained carotid arteries from control and KC-Tie2 mice following Rose Bengal laser treatment. Note the fibrin-platelet rich thrombi with some red blood cells in the lumen of carotid arteries of KC-Tie2 and not control mice (b). *P<0.05 vs control animals. Scale bar = 100 μm.