Figure 5. “Brown” fat in human adults share molecular characteristics of murine beige rather than brown cells.
Expression of beige- and brown-selective genes in hWAT versus hBAT samples from total 11 subjects of two independent cohorts were measured by qPCR. (A) UCP1 expression levels were measured and confirmed to be higher in BAT as compared to WAT. (B) Heatmap summary of relative fold changes in expression of these genes in each subject. Relative gene expression level of 3 beige-selective (C), 3 brown-selective (D) are shown individually. P value was analyzed using Wilcoxom matched pairs signed ranks test.
