Figure 6. Beige selective markers are expressed in human “brown” fat cells residing in supraclavicular regions.
Microscopic images of adult supraclavicular adipose tissue stained with antibodies recognizing CD137 (red, A and C), UCP1 (green, A), TMEM26 (green, B) and perilipin (green, C) as indicated with nuclei stained with DAPI. It is worth noting that in (A) and (B) the expression of both CD137 and TMEM26 in multilocular (see the arrowhead in B), UCP1+ adipocytes (labeled with “BAT”), but the neighboring perilipin-1+, UCP1− adipocytes are CD137− (labeled with “WAT”, see C).
