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. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Dev Biol. 2012 May 8;368(2):181–192. doi: 10.1016/j.ydbio.2012.04.034

Figure 5. ken-mediated CySC and GSC self-renewal is not due to ectopic JAK-STAT pathway activation.

Figure 5

(A, B) Confocal sections through testes immunostained with anti-Stat92E (STAT, green), anti-Vasa (red), and DAPI (blue). (A) In positive control testes with sustained hopTumL expression in the CySC lineage, Vasa-negative somatic cells far away from the hub (not shown) express elevated levels of Stat92E due to ectopic JAK-STAT pathway activation. (B) In testes misexpressing ken in the CySC lineage, Stat92E expression is not detected above background levels in ectopic CySCs or GSCs. Scale bar, 20 m.