Table 3.
Risk factor | Progressors (n=8) | Non-progressors (n=34) | Risk Ratio [95% CI]† | p value |
---|---|---|---|---|
Average age UC onset (yrs) | 28 | 32 | 0.99 (0.93–1.05) | 0.79 |
Onset of UC age ≥ 30 | 3 | 15 | 1.12 (0.25–5.09) | 0.88 |
Average age at LGD (yrs) | 44 | 51 | 0.95 (0.88–1.02) | 0.13 |
Age at LGD ≥ 50 | 2 | 17 | 0.99 (0.10–2.57) | 0.40 |
Duration of UC (yrs) at LGD | 15.5 | 18.5 | 0.95 (0.88–1.02) | 0.17 |
Duration of UC ≥ 20yrs | 3 | 17 | 0.36 (0.07–1.87) | 0.23 |
# biopsies taken (mean) | 39 | 43 | 0.97 (0.92–1.03) | 0.34 |
# of biopsies with LGD(mean) | 2.6 | 1.5* | 2.83 (1.44–5.55)* | <0.01 |
≥2 biopsies with LGD | 6 | 13 | 7.2 (0.86–60.07) | 0.07 |
≥3 biopsies with LGD | 4 | 5 | 5.8 (1.29–26.04) | 0.02 |
Left-sided dysplasia | 4 | 16 | 1.14 (0.25–5.13) | 0.86 |
Visible lesion | 4 | 19 | 0.61 (0.14–2.73) | 0.51 |
Primary Sclerosing Cholangitis | 4 | 7 | 1.78 (0.39–8.11) | 0.45 |
95% Confidence Interval
one outlier patient with 40 biopsies of LGD was excluded from calculations