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. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Dev Biol. 2012 May 15;368(2):214–230. doi: 10.1016/j.ydbio.2012.05.005

Fig. 1.

Fig. 1

Crx and Math5 (βgal) are expressed in overlapping subsets of cells during or shortly after cell cycle exit. (A) Schema comparing the temporal expression patterns and cellular abundance of Crx (red) and Math5 (black) in the retina. (B–C) Sections from E13.5 (B) or E15.5 (C) Math5-lacZ/+ embryos costained for βgal (Math5-lacZ allele), Crx, and EdU following a 4 hour chase in vivo. Many cells coexpress Math5 and Crx (arrowheads), and both factors are expressed in some cells during or shortly after cell cycle exit (EdU+, arrows). Cells initiating expression of Crx or Math5 reflect similar populations of progenitors. RPE, retinal pigmented epithelium; NBL, neuroblastic layer; GCL, ganglion cell layer. Scale bar, 50 µm.