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. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Dev Biol. 2012 May 15;368(2):214–230. doi: 10.1016/j.ydbio.2012.05.005

Fig. 5.

Fig. 5

Widespread Crx>Math5 expression does not alter RGC abundance or retinal histology. (A–C) Sections from E13.5 (A), P0 (B) and P22 (C) non-transgenic (non-Tg) or Crx>Math5-IRES2-Cre (Crx>Math5 Tg) retinas stained for Brn3a (A,B) or rhodamine dextran (C) to mark RGCs, and counterstained with DAPI to mark nuclei. There is non-specific staining in the RPE and vitreous due cross-reactivity of anti-mouse secondary antibodies with mouse IgG. (D) RGC fraction among GCL neurons at P0 and P22. There is no significant difference in the RGC fraction between transgenic (Tg) and control retinas. (E) Low (top) and high (bottom) magnification views of basic fuchsin-and methylene blue-stained plastic sections. The retinal histology is similar in Crx>Math5 Tg and control mice. Scale bar: 50 µm in A–C; 100 µm in E.