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. Author manuscript; available in PMC: 2013 Sep 15.
Published in final edited form as: Int J Cancer. 2012 Apr 4;131(6):E983–E994. doi: 10.1002/ijc.27544

Figure 1. Favorable and unfavorable histology Kenyan WT.

Figure 1

(A) Favorable histology WT showing monophasic blastemal predominance (400X). (B) Triphasic favorable histology WT with nuclear unrest (400X). (C) WT from Patient #3 shows diffuse anaplasia with hyperchromatic nuclei and nuclear gigantism (600X). (D) WT from patient #15 shows diffuse anaplasia, displaying hallmark multipolar mitoses (arrowhead) and nuclear gigantism (600X). (E) Nuclear detection of p53 in favorable histology triphasic WT (400X). Detection is present in both blastema and epithelia, but not stroma. p53 detection was more sparse and less intense in favorable histology specimens when compared with unfavorable histology. (F) Nuclear p53 detection in unfavorable histology WT from Patient #15 (400X).