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. Author manuscript; available in PMC: 2013 Sep 6.
Published in final edited form as: Neuroscience. 2012 May 26;219:183–191. doi: 10.1016/j.neuroscience.2012.05.048

Figure 8. Knockout of sEH eliminates the difference in sensitivity to OGD between cells from males vs. females.

Figure 8

Cortical neurons from wild-type (WT) and sEH knockout (sEHKO) mice were cultured and exposed to OGD on the 10th day in vitro. WT male mice had significantly more cell death after OGD compared with corresponding WT female mice, but this sex difference was not significant in the knockout mice. Average cell death in neurons from male and female embryos was expressed relative to the mean of cell death in males (n=6–8, *p<0.05).