Table 2.

BMI change and lung and SCC UADT cancers.

	Lung Cancer			SCC UADT Cancer
Variables	Ca/Co	Crude OR (95% CI)	Adjusted OR1 (95% CI)	Ca/Co	Crude OR (95% CI)	Adjusted OR2 (95% CI)
BMI at age 21 (kg/m2)
<20.34	187/255	1.00	1.00	111/255	1.00	1.00
20.34 to <22.15	148/259	0.77 (0.59, 1.02)	0.97 (0.69, 1.35)	108/259	0.95 (0.69, 1.31)	0.93 (0.64, 1.34)
22.15 to <24.34	129/262	0.67 (0.50, 0.89)	0.89 (0.63, 1.27)	153/262	1.34 (0.99, 1.80)	1.19 (0.83, 1.72)
≥24.34	134/248	0.73 (0.55, 0.97)	0.93 (0.64, 1.34)	141/248	1.30 (0.96, 1.77)	1.25 (0.86, 1.81)
P trend		0.015	0.611		0.019	0.110
BMI 1yr before interview (kg/m2)
<18.5	18/13	1.89 (0.91, 3.93)	1.31 (0.55, 3.14)	13/13	1.76 (0.80, 3.87)	2.37 (0.95, 5.92)
18.5 to <25	263/360	1.00	1.00	204/360	1.00	1.00
25 to <30	214/397	0.73 (0.58, 0.92)	0.87 (0.66, 1.16)	199/397	0.88 (0.69, 1.12)	0.90 (0.68, 1.20)
≥30	114/257	0.60 (0.46, 0.79)	0.58 (0.41, 0.81)	109/257	0.74 (0.56, 0.99)	0.70 (0.50, 0.98)
P trend		<0.001	0.001		0.014	0.013
BMI change
<−5%  (weight loss)	51/39	1.60 (0.99, 2.61)	1.09 (0.60, 1.98)	51/39	1.69 (1.04, 2.76)	1.32 (0.75, 2.31)
−5% to <+5%	113/139	1.00	1.00	107/139	1.00	1.00
5% to <15%	132/256	0.63 (0.45, 0.87)	0.76 (0.51, 1.13)	114/256	0.57 (0.41, 0.80)	0.61 (0.41, 0.90)
15% to <25%	113/214	0.65 (0.46, 0.91)	0.72 (0.47, 1.09)	105/214	0.63 (0.45, 0.89)	0.69 (0.46, 1.04
25% to <35%	67/153	0.53 (0.36, 0.78)	0.53 (0.33, 0.84)	51/153	0.43 (0.28, 0.64)	0.44 (0.27, 0.71)
>35%	122/222	0.67 (0.48, 0.94)	0.53 (0.35, 0.80)	85/222	0.49 (0.34, 0.70)	0.51 (0.34, 0.78)
P trend*		0.040	0.001		<0.001	0.002

¹Adjusted for age, gender, ethnicity, tobacco smoking status, pack-years, education, calories.

²Adjusted for age, gender, ethnicity, education, tobacco smoking status, pack-years, drinking status, drinking years, calories.

^*Negative BMI change (weight loss) excluded.

BMI: Body Mass Index, SCC: Squamous Cell Carcinoma