Table 2.
Sensitivity | Specificity | Accuracy | P value | Relative Risk | 95% C.I. | ||
---|---|---|---|---|---|---|---|
MH vs NH | |||||||
Modality | Regions of interest | ||||||
PiB | LTL | 68% | 63% | 66% | 0.01 | 1.8 | 1.0-3.5 |
FDG | PCC | 74% | 56% | 66% | 0.04 | 1.9 | 1.0-4.0 |
PiB in LTL + FDG in PCC | 74% | 63% | 69% | 0.004 | 2.6 | 1.1-4.4 | |
SPM peaks | |||||||
PiB | STG | 63% | 63% | 63% | 0.03 | 1.7 | 0.9-3.4 |
FDG | PCC | 74% | 69% | 71% | 0.01 | 2.4 | 1.2-4.8 |
PiB in STG + FDG in PCC | 74% | 69% | 71% | 0.005 | 2.4 | 1.2-4.8 | |
MH vs PH | |||||||
Modality | Regions of interest | ||||||
PiB | PCC | 79% | 50% | 68% | 0.007 | 1.8 | 1.0-4.1 |
FDG | HIP | 79% | 50% | 68% | 0.007 | 1.8 | 1.0-4.1 |
PiB in PCC + FDG in HIP | 79% | 58% | 71% | 0.001 | 1.9 | 1.1-3.5 | |
SPM peaks | |||||||
PiB | PCC | 84% | 50% | 71% | 0.03 | 1.7 | 1.0-2.7 |
FDG | PFC | 95% | 67% | 84% | 0.001 | 2.8 | 1.6-3.7 |
PiB in PCC + FDG in PFC | 84% | 83% | 84% | <0.001 | 5.1 | 1.9-16.0 | |
PH vsNH | |||||||
Modality | Regions of interest | ||||||
PiB | PCC | 58% | 75% | 68% | 0.03 | 2.1 | 0.9-4.6 |
FDG | n.a. | ||||||
SPM peaks | |||||||
PiB | PCC | 75% | 75% | 75% | 0.002 | 3.0 | 1.3-6.1 |
FDG | n.a. |
Abbreviations: HIP = hippocampus, LTL = lateral temporal lobe, PCC = posterior cingulate cortex, PFC = prefrontal cortex, STG = superior temporal gyrus