Skip to main content
. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Neurobiol Aging. 2012 Apr 11;34(1):22–34. doi: 10.1016/j.neurobiolaging.2012.03.002

Table 2.

Group discrimination and relative risk based on PiB- and FDG-PET measures

Sensitivity Specificity Accuracy P value Relative Risk 95% C.I.
MH vs NH
Modality Regions of interest
PiB LTL 68% 63% 66% 0.01 1.8 1.0-3.5
FDG PCC 74% 56% 66% 0.04 1.9 1.0-4.0
PiB in LTL + FDG in PCC 74% 63% 69% 0.004 2.6 1.1-4.4
SPM peaks
PiB STG 63% 63% 63% 0.03 1.7 0.9-3.4
FDG PCC 74% 69% 71% 0.01 2.4 1.2-4.8
PiB in STG + FDG in PCC 74% 69% 71% 0.005 2.4 1.2-4.8
MH vs PH
Modality Regions of interest
PiB PCC 79% 50% 68% 0.007 1.8 1.0-4.1
FDG HIP 79% 50% 68% 0.007 1.8 1.0-4.1
PiB in PCC + FDG in HIP 79% 58% 71% 0.001 1.9 1.1-3.5
SPM peaks
PiB PCC 84% 50% 71% 0.03 1.7 1.0-2.7
FDG PFC 95% 67% 84% 0.001 2.8 1.6-3.7
PiB in PCC + FDG in PFC 84% 83% 84% <0.001 5.1 1.9-16.0
PH vsNH
Modality Regions of interest
PiB PCC 58% 75% 68% 0.03 2.1 0.9-4.6
FDG n.a.
SPM peaks
PiB PCC 75% 75% 75% 0.002 3.0 1.3-6.1
FDG n.a.

Abbreviations: HIP = hippocampus, LTL = lateral temporal lobe, PCC = posterior cingulate cortex, PFC = prefrontal cortex, STG = superior temporal gyrus