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. Author manuscript; available in PMC: 2013 Jul 30.
Published in final edited form as: J Neurosci Methods. 2012 Jun 16;209(1):127–133. doi: 10.1016/j.jneumeth.2012.06.006

Figure 3.

Figure 3

OXT and AVP were readily detectable in PVN dialysates (A). Standard addition experiment to compare MS signal from aCSF and dialysate matrices (B). RT is retention time in min. Peak area is compared for 10 pM standard OXT and AVP in aCSF (left) and a PVN dialysate sample (center). Spiking the dialysate with additional 10 pM peptide resulted in an additive signal (right). Standard curves (1, 10 and 100 pM) were run in both aCSF and dialysate which showed that both OXT (C) and AVP (D) signal intensities were similar regardless of sample matrix. The result shows that the system sensitivity is the same in either aCSF or dialysate samples.