Fig. 7.

Effect of repetitive amphetamine treatment on FM 50-kHz USV rate response profiles in rats categorized by ranking in relation to the median latency time for the first post-drug USV recording session (LR _{USV latency} rats with above-median USV latency, HR _{USV latency} rats with below-median USV latency). The upper panels are for illustration purpose only; hence, for clarity, error bars are not shown. The ANOVA results given below refer to the data shown in the lower panels. Three-way ANOVA—category effect: F _{1, 20} = 1.36, p = 0.26; day effect: F _{3, 60} = 3.83, p = 0.014; post-drug session time effect: F _{1, 20} = 0.53, p = 0.48; day × category interaction effect: F _{3, 60} = 2.84, p = 0.045; category × post-drug session time interaction effect: F _{1, 20} = 0.05, p = 0.82; day × post-drug session time interaction effect: F _{3, 60} = 7.96, p < 0.001; day × post-drug session time × category interaction effect: F _{3, 60} = 1.47, p = 0.23. *p < 0.05, ***p < 0.001 vs. the corresponding day 1 10-min block value; ΔΔΔp < 0.001 vs. the respective day 7 10-min block value; the Tukey test