Table 2.
Schematic overview of 11 iMRI-guided craniotomies for brain tumor resection in nine children
| Case # | Histology | iMRI | epMRI | Postoperative neurological deficit | Follow-up |
|---|---|---|---|---|---|
| 1 | MOA | GTR | GTR | No | Recurrence (next case) |
| 1 (recurrence) | GNTOIa | Intended STR | STR | No | Alive (>5 years) progression free |
| 2 | GB recurrence | GTRb | GTR | No | 11 months |
| 3 | PA | GTRb | GTR | No | Alive (>3 years) |
| 4 | MEP | GTRb | GTR | No | 1 year |
| 5 | PA | GTRb | GTR | Transient dysphasia | Alive (>3 years) |
| 6 | Medullobl | GTR | GTR | No | Alive (>3 years) |
| 7 | GG grade 2 | GTR | GTR | No | Alive (>2 years) |
| 8 | PA | Intended STRb | STR | Cerebellar mutism | Residual (next case) |
| 8 (residual) | PA | GTR | GTR | No | Alive (>3 years) |
| 9 | DNET | GTR? | STR | No | Alive (>1 years) progression free |
DNET dysembryoplastic neuroepithelial tumor, GB glioblastoma, GG ganglioglioma, medullobl medulloblastoma, GNTOI glioneuronal tumor of infancy, GTR gross total resection, GTR? probable GTR, MEP malignant ependymoma, MOA malignant oligoastrocytoma, PA pilocytic astrocytoma, STR subtotal resection
aHistological examination of the resected recurrence revealed a much more differentiated “glioneuronal tumor of infancy”
bIndicates that an increased EOTR was achieved after additional resection as suggested by iMRI