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. Author manuscript; available in PMC: 2013 Sep 6.
Published in final edited form as: Neuroscience. 2012 Jun 4;219:271–279. doi: 10.1016/j.neuroscience.2012.05.064

Figure 2. mGlu5R inhibition in vivo increases the number of proliferative cells in the EGL.

Figure 2

(A) Experimental plan for intraperitoneal (IP) injection of BrdU and MPEP in P7–P9 mice. (B) Mid-sagittal cerebellar section labeled with DAPI indicating the region of quantification between folia V-VI (red box). (C) Bar graphs of the percentage (%) of BrdU-positive cells in the EGL normalized to control following control PBS or MPEP injections. BrdU was injected prior to the first or following the last MPEP injection. *p < 0.05. (D–I) Confocal micrographs of BrdU immunostaining (green, D–E), DAPI counterstaining (red. F–G) and merge (H–I) between folia V–VI from control or MPEP-treated mice. The EGL is outlined with white dotted lines. Scale bar = 50 μm.