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. Author manuscript; available in PMC: 2013 Sep 6.
Published in final edited form as: Neuroscience. 2012 Jun 1;219:92–110. doi: 10.1016/j.neuroscience.2012.05.059

Figure 1. Diverse synaptic backgrounds achieve in vivo-like output spiking.

Figure 1

A. Iso-frequency lines for GPbase. Each point on each line reflects a pair of excitatory and inhibitory input frequencies that generated output spiking at one of the target frequencies (indicated by color). Dashed and solid lines for each color trace reflect the unitary conductance (gain) of the synaptic events composing the synaptic background. B. Iso-frequency lines for the GPNDSK model. C. Representative total excitatory and inhibitory conductance traces (top), total excitatory and inhibitory current traces (middle), and voltage traces (bottom) for synaptic backgrounds (indicated in A) with 1 nS unitary synaptic inputs (C1), 2 nS unitary synaptic inputs (C2), and high frequency inputs (C3) during 30 Hz spiking of the GPbase model. D. Representative traces for the GPNDSK model with a synaptic background (indicated in B) driving 30 Hz spiking.