Figure 1.
IKK-β inhibition of cardiomyocyte hypertrophy and p65 expression in vitro. Murine cardiomyocytes were cultured and stimulated with hypertrophic agonists, leukemia inhibitory factor (LIF) and phenylephrine (PE). Western blot was performed for the hypertrophic marker, β-myosin heavy chain (β-MHC) and total and phosphorylated p65-NF-κB. Blot is representative of 3 separate mouse cardiomyocyte procurements. β-tubulin serves as the loading control.