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Toxicity of IL6(T23)-PE38KDEL administered to mice by intravenous injection.
| Dose (mg/kg) | Treatment schedule | Mortality |
|---|---|---|
| 0.25 | Single dose | 0/10 |
| 0.50 | Single dose | 0/10 |
| 0.75 | Single dose | 3/10 |
| 1.00 | Single dose | 4/10 |
| 1.25 | Single dose | 7/10 |
| 1.50 | Single dose | 10/10 |
| 0.50 | Daily for 10 doses | 2/10 |
| 0.40 | Daily for 10 doses | 0/10 |
