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MTHFR C677T genotype frequencies and the CRC risk.
| Genotypes | Controls (n=370) n (%) |
Cases (n=370) n (%) |
OR (95% CI) | P-value |
|---|---|---|---|---|
| CC | 139 (37.6) | 124 (33.5) | 1 | |
| CT | 178 (48.1) | 167 (45.1) | 1.052 (0.763–1.450) | 0.758 |
| TT | 53 (14.3) | 79 (21.4) | 1.671 (1.094–2.553) | 0.018 |
| CT+TT | 231 (62.4) | 246 (66.5) | 1.194 (0.883–1.614) | 0.249 |
OR, odds ratio; 95% CI, 95% confidence interval. MTHFR, methylenetetrahydrofolate reductase; CRC, colorectal cancer.
