Table 6.

Cost-effectiveness sensitivity (A) and subgroup analysis (B)

	Intervention group (n)	Control group (n)	Cost of intervention (£)	ICER (£)	Bootstrapped one-sided 95% CI for ICER (£)	Probability that intervention is cost effective*
(A) Sensitivity analyses
Base case	395	391	385	12 111	58 881	89%
Mean intervention and control EQ-5D at 6 months as estimate of baseline	395	391	385	6055	37 159	96%
Control group mean EQ-5D value at 6 months as estimate of baseline	395	391	385	7109	24 853	98%
Participant payment of £1 per session	395	391	385–32=353	10 926	69 085	91%
Participant payment of £2 per session	395	391	385–64=321	9741	64 638	92%

	Intervention group (n)	Control group (n)	Incremental cost (bootstrapped 95%CI)	Incremental QALY (bootstrapped 95%CI)	ICER (bootstrapped one-sided 95%CI)
(B) Subgroup analysis
Referral reason
CHD only	307	309	£239 (−51 to 547)	0.0183 (−50.0047 to 0.0416)	£13 060 (117 893)
Mental health (MH) and MH plus CHD	80	76	£596 (−5304 to 1616)	0.058 (0.017 to 0.100)	£10 276 (50 925)
Gender
Male	135	130	£322 (−5180 to 792)	0.0084 (–0.0250 to 0.0400)	£38 333 (254 973)
Female	265	268	£326 (−589 to 761)	0.0362 (0.0111 to 0.0623)	£9006 (390 00)
Age
<44 years	69	71	£68 (−5462 to 678)	0.0656 (0.0137 to 0.1148)	£1037 (16 418)
44–60 years	135	136	£577 (−5176 to 1373)	0.0179 (−0.0194 to 0.0561)	£32 235 (314 108)
>60 years	196	191	£244 (−5131 to 586)	0.0187 (−0.0057 to 0.0424)	£13 048 (153 565)
Adherence
0 weeks	30		£1785 (25 to 4570)	−0.0114 (−0.0680 to 0.0390)	NA
<16 weeks	123		£662 (212 to 1157)	−0.0084 (−0.0384 to 0.0218)	NA
16 weeks	247		–£18 (−5310 to 277)	0.049 (0.0277 to 0.0706)	−£367 (7068)

^*At the £30 000 per QALY threshold.

EQ5D, EuroQol—5 Dimensions; ICER, incremental cost-effectiveness ratio; QUALY, quality adjusted life year.