Table 2.
Mean and SD (unweighted values) for bronchodilator responses for whole study population, healthy and COPD subgroups
| Variables | Study population | Healthy subgroup | COPD GS2+ | COPD GS2+ (without asthma) | ||
| All | Men | Women | Men and women | Men and women | Men and women | |
| FEV1-based measures | N1=10 217 | N1=4826 | N1=5391 | N1=3922 | N1=1009 | N1=745 |
| ΔFEV1 (ml) | 82 (139) | 95 (156) | 70 (120) | 72 (130) | 114 (157) | 104 (153) |
| ΔFEV1i (%) | 3.7 (6.9) | 3.6 (6.5) | 3.8 (7.3) | 3.1 (6.0) | 8.8 (11.9) | 7.7 (11.0) |
| ΔFEV1p (%) | 2.8 (4.8) | 2.7 (4.6) | 2.8 (5.0) | 2.6 (4.8) | 4.2 (5.7) | 3.7 (5.5) |
| FVC-based measures | N2=9546 | N2=4560 | N2=4986 | N2=3593 | N2=976 | N2=723 |
| ΔFVC (ml) | 0 (237) | 4 (257) | −4 (217) | −21 (219) | 153 (280) | 138 (273) |
| ΔFVCi (%) | 0.5 (7.9) | 0.5 (6.9) | 0.5 (8.7) | −0.3 (7.4) | 6.9 (12.2) | 6.2 (11.9) |
| ΔFVCp (%) | 0.1 (6.6) | 0.2 (5.9) | 0 (7.3) | −0.5 (6.7) | 4.4 (7.9) | 4.0 (7.6) |
ΔFEV1 (ml) and ΔFVC (ml) are absolute change after bronchodilator; ΔFEV1i and ΔFVCi are change as a per cent of initial value.
ΔFEV1p and ΔFVCp are change as per cent of predicted value. N1 is number with non-missing FEV1 values and N2 is number with non-missing FVC values.
COPD GS2+ = FEV1/FVC <0.7 and FEV1% predicted<80%; COPD GS2+ (without asthma) = post-bronchodilator spirometrically defined COPD excluding those with self-reported asthma.
COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.