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Effect of indomethacin (10 µM) or NS-398 (10 µM) on the concentration-dependent relaxation to ACh in segments of mesenteric resistance arteries from (A) 3-month-old O-CR, (B) 3-month-old ODR, (C) 6-month-old O-CR, (D) 6-month-old ODR, (E) 12-month-old O-CR and (F) 12-month-old ODR. Results are expressed as mean ± SEM; n= 7–8 animals in each group.
